What is IsletCore?
-established in late 2010 with support from the Alberta Diabetes Foundation and the University of Alberta, we have isolated more than 57 million islets for research from more than 225 human organ donors as of June 2017.
-a human islet isolation, research, distribution, and biobanking facility located in a state-of-the art laboratory on the 5th floor of the Alberta Diabetes Institute.
-our goal is to isolate, bank, and distribute human islets specifically for research purposes from donor pancreas that would not otherwise be used in clinical transplantation.
-our research-specific focus allows the use of organs from donors with type 1 diabetes (T1D) and type 2 diabetes (T2D), as well as other non-standard donors so that researchers can better understand the processes contributing to islet health and dysfunction.
-we isolate and distribute human islets from a range of donor types (breakdown shown at right) to academic laboratories for the study of diabetes.
-we bank functional islets by cryopreservation, for future research and use with emerging technologies to facilitate diabetes research.
-paraffin-embedded biopsies, and functional data, are available for all of the donors.
-if you are interested to receive research material from our program please contact Dr. Patrick MacDonald (pmacdonald[at]ualbrta.ca) or our coordinator Dr. Jocelyn Manning Fox (jm33[at]ualberta.ca).
Update and Statistics
-as of Early-2017 we have isolated ~57 million islet equivalents (IEQ) and distributed >22 million IEQ to laboratories across Canada, the US, and overseas.
-following on our recent demonstration of the utility of cryopreserved human islets for research (here), we have banked >22 million IEQ for future study.